Retinocytoma/retinoma: comparative analysis of clinical features in 78 tumors and rate of transformation into retinoblastoma over 20 years.

Purpose To explore clinical features and long-term outcomes in patients with retinocytoma/retinoma. Methods The medical records of patients with retinocytoma/retinoma over a 20-year period were reviewed retrospectively to compare patient age at presentation ( Results Of 2,021 patients with retinoblastoma, 62 (3%; median age, 5 years; 85% white; 58% male) had 78 tumors: 54 retinocytoma (69%) and 24 retinoma (31%). Median basal tumor diameter was 6.0 mm; mean thickness, 2.3 mm. Younger patients ( Conclusions In our study cohort, the rate of retinocytoma/retinoma transformation into retinoblastoma increased from 2 to 10-20 years of age. The only factor predictive of transformation was increasing tumor thickness.