Progress of Drug and non-Drug Treatment in Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathy(DPN) is one of the common chronic complications in diabetic patients. Patients with DPN present variable symptoms and physical findings, ranging from asymptomatic loss of tendon reflex to severe painful neuropathy, even lead to disability. It seriously lower the quality of diabetic patients’ life. Because of its etiology and pathogenesis were not yet fully understood, the treatment has been tending to diversification. Strict glycemic control is a precondition, then we shuold focus on the elimination of the etiology, relieve the symptoms, prevention and treatment the complications.Such as improving vascular function, adjusting the metabolic disorders, relieving pain and other methods. Due to the limitations of western drug treatment, also, non-drug treatment is easy to operate with clear effect and little side effects, current studies of non-drug treatment tend to increase gradually, such as electric acupuncture therapy, autologous bone marrow stem cells implantation, hyperbaric oxygen therapy and other methods．The combination of drug and non-drug treatment can improve the curative effect of DPN. This review summarize the progress of drug and non-drug treatment for DPN in the recent years.