Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway

Grace A. Chappell,Julia E. Rager,Jeffrey C. Wolf,Milos Babic,Kyle J. LeBlanc,Caroline L. Ring,Mark A. Harris,Chad M. Thompson

Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway

2019

Grace A. Chappell
Julia E. Rager
Jeffrey C. Wolf
Milos Babic
Kyle J. LeBlanc
Caroline L. Ring
Mark A. Harris
Chad M. Thompson

Carcinogenesis of the small intestine is rare in humans and rodents. Oral exposure to hexavalent chromium (Cr(VI)) and the fungicides captan and folpet induce intestinal carcinogenesis in mice. Pre...

Keywords:

Gene expression
Carcinogen
Biology
Small intestine
Bioinformatics
Endocrinology
Internal medicine
Gene
Adverse Outcome Pathway
Cancer research
Carcinogenesis
Captan
Mode of action
Transcriptome

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