Use of negative thyroid transcription factor (TTF-1) status to predict for negative epidermal growth factor receptor (EGFR) mutations (Mts) status with a high negative predictive value (NPV) in patients (pts) with adenocarcinomas (AC) of the lung.

Neeta Somaiah,Elizabeth Garrett-Mayer,X. Huang,Amy E. Wahlquist,K. Danenberg,George R. Simon

Use of negative thyroid transcription factor (TTF-1) status to predict for negative epidermal growth factor receptor (EGFR) mutations (Mts) status with a high negative predictive value (NPV) in patients (pts) with adenocarcinomas (AC) of the lung.

2011

Neeta Somaiah
Elizabeth Garrett-Mayer
X. Huang
Amy E. Wahlquist
K. Danenberg
George R. Simon

7530 Background: TTF-1 is expressed in about 72% of ACs. EGFR Mts are present in 10-15% of unselected pts with AC. High TTF1 expression and EGFR Mts are associated with female sex, never-smoking st...

Keywords:

Pathology
Epidermal growth factor receptor
Lung
Medicine
Thyroid Transcription Factor
female sex
predictive value
egfr mutation
in patient

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