[Application of immuno-biochemical indices for the identification of the chronic pathology of the upper respiratory tract].

A comprehensive survey of organized children aged 14-17 years residing in the industrial centers with moderate and high levels of air pollution was performed. On the base of the examination of otorhinolaryngologist in the each of cities there was selected the group of schoolchildren with chronic pathology of the upper respiratory tract at the stage of remission. In these groups there was performed the assessment of the informativeness of immuno-biochemical indices for the identification of pathology caused by the impact of man-made factors. The most informative (relative content of autoantibodies to β2-glycoprotein-1, the average individual immunoreactivity, erythrocyte sedimentation rate, level of α1-antitrypsin) were used in the mathematical model, on the based of which it was possible to calculate the diagnostic coefficient, allowing to identify in the groups observed by ourselves, chronic pathology of upper respiratory tract, formed under the influence of ambient air pollution. The above approach can be used in the formation groups for health promotion of children exposed to the negative impact.