Wegenersche Granulomatose unter dem klinischen Bild einer Vasculitis allergica
2001
Wegener's granulomatosis is a rare disease classically characterized by a necrotizing and granulomatous inflammation of the upper and lower respiratory tract, necrotizing glomerulonephritis and systemic vasculitis of small and medium sized vessels. Cutaneous manifestations are observed in 20-50% of cases often resembling pyoderma. We report here on a 72 years old female patient in whom the cutaneous symptom of a histological confirmed leukocytoclastic vasculitis led to the diagnosis of Wegener's granulomatosis. She had also developed the characteristic symptom of a saddle nose and suffered from relapsing keratitis. Clinical symptoms, diagnostic procedure and therapeutic options are discussed.
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