Exploring the combination characteristics of lumefantrine, an antimalarial drug and human serum albumin through spectroscopic and molecular docking studies

Kabiru Abubakar Musa,Nor Farrah Wahidah Ridzwan,Saharuddin B. Mohamad,Saad Tayyab

Exploring the combination characteristics of lumefantrine, an antimalarial drug and human serum albumin through spectroscopic and molecular docking studies

2020

Kabiru Abubakar Musa
Nor Farrah Wahidah Ridzwan
Saharuddin B. Mohamad
Saad Tayyab

ABSTRACTBinding of lumefantrine (LUM), an antimalarial drug to human serum albumin (HSA), the main carrier protein in human blood circulation was investigated using fluorescence quenching titration...

Keywords:

Titration
Biochemistry
Human serum albumin
Chemistry
Docking (molecular)
Quenching (fluorescence)
Lumefantrine
Drug
Fluorescence spectroscopy
blood circulation
Ligand (biochemistry)
Hydrophobic effect
Circular dichroism
Binding site
Crystallography

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