Single Nucleotide Polymorphisms of the Pregnane X Receptor Gene in Han Chinese and a Comparison with Other Ethnic Populations

Xueding Wang,Xiao-Ying Deng,Jie Chen,Jiali Li,Xiao Chen,Li-zi Zhao,Yan Lu,Balram Chowbay,Qi-Biao Su,Min Huang,Shu-Feng Zhou

Single Nucleotide Polymorphisms of the Pregnane X Receptor Gene in Han Chinese and a Comparison with Other Ethnic Populations

2008

Xueding Wang
Xiao-Ying Deng
Jie Chen
Jiali Li
Xiao Chen
Li-zi Zhao
Yan Lu
Balram Chowbay
Qi-Biao Su
Min Huang
Shu-Feng Zhou

The pregnane X receptor (PXR/NR1I2) gene is a master regulator for a number of cytochrome P450s (CYPs) and drug transporters. This study aimed to detect the single nucleotide polymorphisms (SNPs) of t

Keywords:

Pharmacogenomics
Cytochrome
Pregnane X receptor
Regulator
Gene
Single-nucleotide polymorphism
Polymorphism (computer science)
Polymerase chain reaction
Molecular biology
Chemistry
Genetics
Ethnic populations
han chinese
Transporter

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