Is there a relationship between mean platelet volume and the severity of coronary ectasia

Mean platelet volume (MPV) is an indicator of platelet activation that is elevated in patients with coronary artery ectasia (CAE). We aimed to research relationship between MPV and the severity of coronary ectasia. The reports of 6,377 patients who underwent elective coronary angiography screening between January 2011 and January 2015 were reviewed. After exclusion, 117 patients with isolated CAE were included in this study. The severity of CAE was divided into four types according to the Markis classification. There was no significant difference in age, sex, hypertension, diabetes mellitus, smoking, or family history between the CAE and normal angiogram groups (P>0.05). MPV was significantly higher in patients with CAE than the control group (11.14 ± 1.13 vs. 9.82 ± 0.90 fL, P 10.85 fL may indicate the presence of CAE.