Progress on Vaccine Adjuvant CpG ODN
2011
Synthetic oligodeoxynucleotides(ODN) containing unmethylated CpG motifs mimic the immunostimulatory activity of bacterial DNA.CpG ODN directly stimulate a variety of immunological effects.CpG ODN is used as vaccine adjuvants,where they increase the vaccine-specific immune responses and the mucosal immune responses.Ongoing clinical studies indicate that CpG ODN are safe and well-tolerated when administered as adjuvants to animals.
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