MP19-14 FERTILITY-RELATED QUALITY OF LIFE, GONADAL FUNCTION, AND ERECTILE DYSFUNCTION IN MALE PARTNERS OF COUPLES WITH UNEXPLAINED INFERTILITY

AbstractPurpose:We sought to determine whether lower fertility-related QOL or depression in men of couples with unexplained infertility is associated with low total testosterone (TT) levels, abnormal semen quality, or erectile dysfunction (ED).Materials and Methods:This study is a secondary analysis of a large, multicentered, randomized controlled trial for couples with unexplained infertility. Male partners had a baseline semen analysis, fasting TT and gonadotropin levels, and completed the Fertility-Related QOL (FertiQOL), Patient Health Questionnaire 9 (PHQ-9), and International Index of Erectile Function (IIEF) surveys. The primary outcomes were TT (low TT defined as <264 ng/dL), semen parameters, and IIEF score. Multivariable logistic regression analyses adjusted for age, race, BMI, education, smoking, alcohol use, length of infertility, and comorbidity.Results:708 men (mean age 34.2 ± 5.6) were included. Fifty-nine (8.3%) men had a PHQ-9 score (≥5) consistent with depression, 99 (14.0%) had low TT, ...