Genetic control of drug resistance: Assignment ofama-1 to Chinese hamster chromosome 7, confirmation of assignment of genes coding for TK, GALK, and ACP to chromosome 7, and tentative assignment of TPI to chromosome 8

The gene which specifies a subunit of RNA polymerase II, ama-1,is assigned to chromosome 7 in the Chinese hamster. The assignment of genes coding for TK, GALK, and ACP to chromosome 7 is confirmed, with a provisional regional assignment of TK and GALK to 7q. On the basis of one clone with six subclones, a provisional assignment of TPI to Chinese hamster chromosome 8 is made. With the assignment of tkand ama-1to chromosome 7 in the CHO cell line Amal, this chromosome is shown to have two selectable markers.