Interferon therapy in cildren with chronic hepatitis and chronic renal failure treated with dialysis

The HCV proliferation occurs in patients with chronic hepatitis type C on hemodialysis treatment after the kidney graft. The replication markers of HBV also occurs in patients after kidney graft. 35 children were examined. Among HBV infected children the replication phase was in 1 child (3%), nonreplication phase in 2 children (6%). 12 children had a signs of chronic hepatitis type C, 4 children (11.4%) of double active infection of HBV and HCV. The aim of this study was a preliminary evaluation of interferon alpha treatment (INF-alpha) of chronic hepatitis in dialysed children. Despite of high costs of treatment, it is necessary to begin an interferon alpha therapy before renal graft.