8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions.

Julio Leon,Kunihiko Sakumi,Erika Castillo,Zijing Sheng,Sugako Oka,Yusaku Nakabeppu

8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions.

2016

Julio Leon
Kunihiko Sakumi
Erika Castillo
Zijing Sheng
Sugako Oka
Yusaku Nakabeppu

8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions

Keywords:

DNA glycosylase
Phosphoric monoester hydrolases
Cerebral cortex
8-Oxoguanine
Guanine
Mitochondrial DNA
Biochemistry
Oxidative phosphorylation
Biology
Mitochondrion
Molecular biology
Neurite
Oxidative stress
Neurodegeneration

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