Диагностическое значение фактора некроза опухоли-альфа и полиморфизма его гена (g4682a) в прогрессировании цирроза печени

Aim. The aim of the study was to assess the diagnostic value of tumor necrosis factor alpha (TNF-α) and polymorphysm of its gene TNF-A (G4682A) in hepatic cirrhosis (HC) progression. Materials and methods. Eighty one persons with HC and 81 healthy donors were examined. Blood TNF-α concentration and polymorphism of gene TNF-A (G4682A) were estimated. Results. Serum TNF-α level was increased in 99 % of HC patients as compared with the control group ( p