Analysis of signal transduction pathways involved in anti-CD30 mAb-induced human eosinophil apoptosis.

Kenji Matsumoto,Maki Terakawa,Shuhei Fukuda,Hirohisa Saito

Analysis of signal transduction pathways involved in anti-CD30 mAb-induced human eosinophil apoptosis.

2010

Kenji Matsumoto
Maki Terakawa
Shuhei Fukuda
Hirohisa Saito

Background: Activation of cell surface CD30 by immobilized anti-CD30 monoclonal antibodies (mAbs) induces extremely rapid and intense apoptosis in human eosinophils in vitro. This a

Keywords:

Mitogen-activated protein kinase
Eosinophil
CD30
Immunology
Annexin
Apoptosis
Programmed cell death
Signal transduction
Cell biology
Monoclonal antibody
Molecular biology
Biology
Kinase
Wortmannin
Protein kinase C
p38 mitogen-activated protein kinases

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