Efficient Synthesis of O-Succinimidyl-(tert-Butoxycarbonylamino)methyl Carbamates Derived from α-Amino Acids Accelerated by Ultrasound: Application to the Synthesis of Ureidodipeptides

Vommina V. Sureshbabu,Naremaddepalli S. Sudarshan,Kantharaju

Efficient Synthesis of O-Succinimidyl-(tert-Butoxycarbonylamino)methyl Carbamates Derived from α-Amino Acids Accelerated by Ultrasound: Application to the Synthesis of Ureidodipeptides

2008

Vommina V. Sureshbabu
Naremaddepalli S. Sudarshan
Kantharaju

The synthesis of O-succinimidyl-(tert-butoxycarbonylamino)methyl carbamates employing isocyanates made through the Curtius rearrangement of Boc-amino acid azides in the presence of N-hydroxysuccinimide under the influence of ultrasound is described.

Keywords:

Organic chemistry
Curtius rearrangement
Amino acid
N-Hydroxysuccinimide
Chemistry
Biochemistry
ultrasonic irradiation
Ultrasound

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