IVIg-mediated amelioration of murine ITP via FcγRIIb is not necessarily independent of SHIP-1 and SHP-1 activity

Crow et al[1][1] state that the protective effect of intravenous immunoglobulins (IVIg's) in murine idiopathic thrombocytopenia (ITP) requires FcγRIIb but not its signaling molecules Src homology 2 domain-containing inositol polyphosphate phosphatase-1 (SHIP-1), Src homology 2 domain-containing