Способ моделирования нарушенной посттравматической регенерации костей голени

There has been developed a model of posttraumatic regeneration of diaphysis of tibia with the formation of pseudarthrosis to the 20th day and the absence of adhesions to the 50th day. Violation of consolidation of shin bone causes the formation of connective tissue in the area of the cartilage defect to the 10th day and the absence of consolidation to the 50th day, i.e. the formation of a pseudarthrosis. The model developed by its characteristics is as close as possible to the actual clinical process. The reproducibility of the model is 100%. The standardization of the model obtained is achieved by using the same type, breed, sex, age and weight of the animals, as well as by the given parameters, provided the original external fixation device. The model can be used in chronic experiments to study the mechanisms of formation and development of nonunion fractures of long bones in the lower extremities of laboratory animals.