Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release
2009
Unlike the involvement of the synaptotagmin (syt) family of proteins in calcium-triggered membrane fusion, the precise function and localization of syt-IV are not clear. Here the authors demonstrate that syt-IV is present in BDNF-containing vesicles and regulates axonal/dendritic release of BDNF, which in turn modulates long-term potentiation in hippocampal neurons.
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