Relationship between left ventricular ejection fraction and the glomerular filtration rate, and their impact on death during cardio-renal syndrome at University Hospital of Brazzaville (Congo)

Background Cardiorenal syndrome (CRS) is the association of heart failure (HF) and renal failure (RF). This association is poor in terms of prognosis. Purpose To determine the correlation between glomerular filtration rate (GFR) and left ventricular ejection fraction (LVEF), and their impact on death. Methods This cross-sectional study, by document analysis, was conducted from January 2016 to December 2017 in the departments of cardiology and nephrology at University Hospital of Brazzaville. We had included the patients with association HF and RF. Results One hundred and eighty-six patients, 105 men (56.5%) were included. The mean age was 58 ± 15.5 years (range: 17 to 90 years). The risk factors were: hypertension (n = 128, 68.8%), diabetes (n = 56, 30%) and alcoholism (n = 23, 12.4%). At admission, the mean serum creatinine level was 47.2 ± 55.5 mg/L (range 16 to 136) and the mean GFR was 24.5 ± 22.8 ml/min (range: 2.1 and 100). In echocardiography, mean LVEF was 47.8 ± 18.2% (range: 22 to 87). LVEF   100 mg/L (n = 9, 50%, OR 11.8, CI95% 4–35, P   100 mg/L was independent determinant of death (OR 10.7, 95% CI 2.3–44, P = 0.001). Conclusion The prognosis of CRS is poor because the direct relation of blood creatinine level and death. Indeed, due to the limited access to dialysis in our country, the overall care of patients remains difficult. The extension and implantation of dialysis centers in our country remain the major challenges.