The functions and mechanisms of microecological agents in weaning piglet intestine

The high mortality rate of weaning piglets caused by diarrhea is an important issue that hinders the development of pig industry. Weaning piglets are susceptible to pathogenic bacteria, viruses and other stresses which lead to gastrointestinal dysfunction due to their immature intestinal barrier and immune system. Antibiotics can increase economic efficiency by improving the status of animal husbandry, however, the abuse of antibiotics has led to the emergence of antibiotic resistant strains, which seriously injured the human health. As a result, it is urgent to develop safe alternatives to reduce or replace antibiotics. Microecological agents are safe, drug-resistance-free and have non-toxic side effects and positive impact on intestinal health of animals. Therefore, understanding the mechanisms of microecological agents in improving intestinal health has important implications for the effective use of them. This review summarizes the cause of diarrhea and the major probiotic functions and mechanisms of microecological agents in weaning piglets.