Abstract WP130: Comparison of VerifyNow System and Thrombelastography for Assessing Asprin Response in Stroke Patients in China

Objectives: The aim of the study was to compare the consistency of VerifyNow System and thrombelastography (TEG) in stroke patients treated with asprin in China. Methods: Patients hospitalized in Changhai Hospital and Yueyang Hospital with acute ischemic stroke were randomly enrolled into treatment with a 100-mg daily maintenance dose of asprin. Platelet reactivity was evaluated by VerifyNow System (Accumetrics Inc.) and TEG (Hemonetics Corporation) at the same time on the 5th-7th day of asprin treatment. Patients with asprin low response (ALR) were detected by using the methods and criteria published earlier (ARU ≥550 assayed by VerifyNow System or Inhibition% ≤50% measured by TEG). All patients were followed up for 2 years and clinical endpoint was ischemic events, including major adverse cardiac events (MACE), recurrence of stroke, transient ischemic attack (TIA),and the composite of vascular death. Results: Totally 94 patients were enrolled for the study and there were wide varieties in parameters of ...