B5. A cross comparison study of USCOM® and transthoracic echocardiography in pregnancy

AbstractIntroduction: There is a paucity of data regarding the accuracy, reliability and reproducibility of non-invasive cardiac output monitors in pregnancy. The aim of this study was to compare cardiac output estimations obtained by USCOM® against those obtained by 2-dimensional transthoracic echocardiography (TTE).Methods: Prospective, observational study in which 114 healthy pregnant and postpartum women had haemodynamic indices obtained by USCOM® and TTE. Accuracy and precision statistics (Bland Altman analysis) are presented as bias, precision, 95% limits of agreement (LOA) and mean percentage difference (MPD). Intraobserver repeatability and interobserver reproducibility of USCOM was assessed in 67 and 40 subjects, respectively.Results: USCOM® had a positive bias ranging from 0.4 to 0.9 L/min. The MPD of USCOM® was 28% in the third trimester cohort, which meets the current level of <30% for clinical acceptability. However, we found no agreement in the first, second trimester or postpartum groups (M...