Табакокурение и функциональное состояние респираторной системы у больных хронической обструктивной болезнью легких

2014 
The aim of the research. Analysis of the impact of smoking on the basic parameters of the functional state of the respiratory system and the severity of COPD. Materials and methods. Were analysed of histories of male patients with COPD, treated in pulmonology center OKB № 4 in Chelyabinsk. Were evaluated the main risk factors for COPD, in particular the fact of smoking, experience and smoker index (IKCH). All patients had conducted a comprehensive clinical examination, which included clinical assessment complaint history, physical, laboratory and instrumental investigations. Was done pulse oximetry; ERF, total body plethysmography. Were analyzed correlations influence smoker index and smoking duration to the severity of COPD and FEV1 and m IT. Results. Cough is one of the most early respiratory symptoms of COPD, and has a significant increase in duration depending on the duration of the disease (r = 0,63, p <0,05) and COPD severity (r = 0,69, p <0, 05). As the duration of smoking increased, the severity of COPD has steady tendency to growth. As the duration of smoking and IKCH is increased, a significant progression of the severity of COPD and decrease in FEV1 is also increased. Conclusion. Seniority of smoking significantly affect to the onset of respiratory manifestations of COPD and the deterioration of basic functional parameters of the respiratory system.
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