Abstract 13610: Endothelial Cu Transporter Atp7a Promotes Vegfr2 Signaling and Post-ischemic Neovascularization via Regulating Autophagy

Dipankar Ash,Sudhahar Varadarajan,Seock-Won Youn,Mustafa N. Okur,John P OBrien,Malgorzata McMenamin,Xuexiu Fang,Yali Hou,Jack H. Kaplan,Tohru Fukai,Masuko Ushio-Fukai

Abstract 13610: Endothelial Cu Transporter Atp7a Promotes Vegfr2 Signaling and Post-ischemic Neovascularization via Regulating Autophagy

2020

Dipankar Ash
Sudhahar Varadarajan
Seock-Won Youn
Mustafa N. Okur
John P OBrien
Malgorzata McMenamin
Xuexiu Fang
Yali Hou
Jack H. Kaplan
Tohru Fukai
Masuko Ushio-Fukai

Background: VEGFR2 (KDR/Flk1) signaling in endothelial cells (ECs) plays a central role in angiogenesis. Copper (Cu) is essential micronutrient and has been implicated in angiogenesis. The P-type A...

Keywords:

Autophagy
Cancer research
Angiogenesis
Transporter
ATP7A
Medicine
VEGF receptors
ischemic injury
Neovascularization

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