Effect of Ginkgo biloba special extract EGb 761 ® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers

Gregor Zadoyan,Dennis Rokitta,Stephan Klement,Angelika Dienel,R. Hoerr,Thomas Gramatté,Uwe Fuhr

Effect of Ginkgo biloba special extract EGb 761 ® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers

2012

Gregor Zadoyan
Dennis Rokitta
Stephan Klement
Angelika Dienel
R. Hoerr
Thomas Gramatté
Uwe Fuhr

Purpose We assessed the human in vivo metabolic drug interaction profile of Ginkgo biloba extract EGb 761® with respect to the activities of major cytochrome P450 (CYP) enzymes.

Keywords:

Drug interaction
Medicine
Enzyme inducer
Enzyme
Ginkgo biloba
Cytochrome P450
In vivo
Pharmacology
Ginkgolides
Ginkgo
Cytochrome P-450 Enzyme Inhibitors

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