Modification of a domiciliary ventilator to increase FiO2: an off-label modification which may be of value in COVID-19.

Although nasal continuous positive airway pressure or non-invasive ventilation is used to manage some patients with acute lung injury due to COVID-19, such patients also demonstrate increased minute ventilation which makes it hard, if the device is used in line with the manufacturer's instructions, to achieve adequate oxygen delivery In addition, if a hospital contains many such patients, then it is possible that the oxygen requirements will exceed infrastructure capacity Here we describe a simple modification of two exemplar ventilators normally used for domiciliary ventilation, which substantially increased the fraction of inspired oxygen (FiO(2)) delivered