A Facile Synthesis of N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3 yl)oxy)acetohydrazides

5-bromo 2,3-diamino pyridine and ethyl pyruvate react each other to form 7-bromo-2-methylpyrido[2,3-b]pyrazin-3-ol (1) which further reacts with ethyl chloroacetate and form ethyl 2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetate (2). Compound 2 on reaction with hydrazine hydrate gives 2-((7-bromo-2-methyl pyrido[2,3-b]pyrazin-3-yl)oxy)acetohydrazide (3), which on condensation with different aldehydes produce N'-Arylidene-2-((7-bromo-2-methyl pyrido[2,3-b]pyrazin-3-yl)oxy) acetohydrazides (4a-e).