DIELS-ALDER-REAKTIONEN VON VINYLINDOLEN MIT ARIN UND 1,4-BENZOCHINONEN : NEUE POTENTIELLE DNA-INTERKALATOREN

Diels-Alder reactions of 2- and 3-vinylindoles with aryne, 1,4-benzo- and 1,4-naphtho-quinone lead to new six-ring annellated carbazoles. Molecular modeling studies predict that the compounds with coplanar framework are able to intercalate with the B-DNA.