Disruption of PLTP (Phospholipid Transfer Protein)-Mediated HDL (High-Density Lipoprotein) Maturation Reduces SR-BI (Scavenger Receptor BI) Deficiency–Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications

Menno Hoekstra,Ronald J. van der Sluis,Reeni B. Hildebrand,Bart Lammers,Ying Zhao,Domenico Praticò,Theo J.C. van Berkel,Patrick C. N. Rensen,Sander Kooijman,Matti Jauhiainen,Miranda Van Eck

Disruption of PLTP (Phospholipid Transfer Protein)-Mediated HDL (High-Density Lipoprotein) Maturation Reduces SR-BI (Scavenger Receptor BI) Deficiency–Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications

2020

Menno Hoekstra
Ronald J. van der Sluis
Reeni B. Hildebrand
Bart Lammers
Ying Zhao
Domenico Praticò
Theo J.C. van Berkel
Patrick C. N. Rensen
Sander Kooijman
Matti Jauhiainen
Miranda Van Eck

Objective: We tested the hypothesis that enlarged, dysfunctional HDL (high-density lipoprotein) particles contribute to the augmented atherosclerosis susceptibility associated with SR-BI (scavenger...

Keywords:

Biochemistry
Scavenger receptor
Endocrinology
HDL - High density lipoprotein
Phospholipid transfer protein
Diabetes mellitus
Hypertriglyceridemia
ATHEROSCLEROSIS SUSCEPTIBILITY
Internal medicine
Biology
Lipoprotein
Scavenger
High-density lipoprotein

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