17BETA -HYDROXYSTEROID DEHYDROGENASE (HSD)/17-KETOSTEROID REDUCTASE (KSR) FAMILY; NOMENCLATURE AND MAIN CHARACTERISTICS OF THE 17HSD/KSR ENZYMES

A number of enzymes possessing 17‚hydroxysteroid dehydrogenase/17-ketosteroid reductase (17HSD/KSR) activities have been described and cloned, but their nomenclature needs specification. To clarify the present situation, descriptions of the eight cloned 17HSD/KSRs are given and guidelines for the classification of novel 17HSD/KSR enzymes are presented.