Küçük hücreli dýþý akciðer kanserinde cilt metastazý: Beþ olgu sunumu ve literatürün gözden geçirilmes i

Cutaneous metastases from non-small cell lung cancer: Report of five cases and review of the literature Metastasis to the skin from lung cancer is much rare than metastasis to other organs and the reported incidence of skin metastases from lung cancer varies from 1-12 %. It may manifest as an initial finding in 7-23.8 % of patients with lung cancer. Five cases are diagnosed as cutaneous metastasis among 257 patients with lung cancer (1.94 %) followed in our department in the period from 2003 to 2007. The male/female ratio was 4/1 and the median age was 64 years (range; 55-80 y). Primary tumor was diagnosed as nonsmall cell lung cancer in all cases. The histopathologic subtypes were the adenocancer and epidermoid cancer in two cases. In one of the patients, skin metastasis was detected after one month from the diagnosis of lung cancer. All patients had an advanced metastatic disease at the time of diagnosis. The mean survival time was 2.4 months after the diagnosis of skin metastasis. Skin metastasis becomes apparent with the progression of the cancer and it is a harbinger of the poor prognosis and the terminal stage of the disease. Therefore an excisional biopsy must be done from every new developed skin lesion in the smokers even if they had a history of lung cancer or not.