Choroidal blood flow in central serous chorioretinopathy (CSC)

Purpose Central serous chorioretinopathy (CSC) has been linked to alterations in perfusion and metabolism. In the present study we investigated arterial and venous oxygen saturation in patients with active CSC and compared it to the data in healthy subjects. Methods A total of 13 subjects with active CSC and 13 healthy age- and sex-matched control subjects were included in this study. Retinal arterial and venous oxygen saturation was measured in an annular area centered at the optic disk using the Imedos Oxygen Module for the Retinal Vessel Analyzer (RVA). Results No significant difference was observed between the patients with CCS and healthy control subjects. This was the case for retinal arterial oxygen saturation (95.0 ± 4.5 % in patients with CCS, 96.2 ± 4.2 %; p = 0.463) and for retinal venous oxygen saturation (66.6 ± 5.5 % in patients with CCS, 63.7 ± 6.1 %; p = 0.392). Conclusion Previous studies have shown that CSC is associated with abnormalities in choroidal blood flow regulation. Our data indicate, however, that retinal oxygenation is normal in CSC patients during the active phase.