Lysosomal enzyme activity in human aqueous humor

Abstract Activity of the lysosomal enzymes N -acetyl- β -D-hexosaminidase, α-D-mannosidase, β-D-glucuronidase, and β-D-galactosidase was detected in aqueous humor from eyes undergoing intraocular surgery. There was no correlation between lysosomal enzyme activity and age. Lysosomal enzyme activity in human aqueous humor most likely reflects the total amount of lysosomal enzyme activity released by ocular tissues surrounding the anterior chamber including the cornea, trabecular meshwork, ciliary body, iris, and lens. Their release into aqueous humor may have a role in regulating aqueous outflow in normal and glaucomatous eyes.