P290: A case of eccrine porocarcinoma

Eccrine porocarcinoma is a rare type of skin cancer arising from sweat glands, represents only 0.005% of epithelial cutaneous neoplasms. It generally present as a single, asymptomatic, nondescript cutaneous lesion on the lower extremities of older adults. The exact etiology of porocarcinoma is unknown. However, it is believed to either arise de novo or by malignant degeneration of a longstanding poroma. Risk factors for eccrine porocarcinoma include family history, immunosuppression, and ultraviolet radiation (UVR). The only way to be sure of the diagnosis is to take biopsy of the tumor. Primary treatment consists of excising the tumor. Surgery is curative in up to 80% of cases. However, about 20% of patients will have local recurrence and metastasis. A 49-year-old male patient visited our department with 2x1.5x1cm sized black colored verrucous surfaced mass on suprapubic region. The onset was about 4years ago. He had no symptoms. Biopsy specimen showed irregular cords and lobules of polygonal basaloid tumor cells that proliferate within the dermis in an asymmetric fashion, also presence of ductal and eccrine differentiation and cytological pleomorphisms. There is no demonstrable metastatic lesion on imaging study. We consulted to department of general surgery for total excision. Herein, we report a rare case of eccrine porocarcinoma.