Preliminary study of region-of-interest image reconstruction with intensity weighting in cone-beam CT using iterative algorithm
2014
In computed tomography (CT) imaging, radiat ion dose delivered to the patient is one of the major concerns. Many CT
developers and researchers have been making efforts to reduce radiat ion dose. Spars e-view CT takes project ions at
sparser view-angles and provides a viable option to reducing radiation dose. Sparse-view CT inspired by a compressive
sensing (CS) theory, which acquires sparsely sampled data in projection angles to reconstruct volumetric images of the
scanned object, is under active research for low-dose imaging. Also, region of interest (ROI) imaging method is one of
the reasonable approaches to reducing the integral dose to the patient and the risk of overdose. In this study, we
combined the two approaches together to achieve an ultra-low-dose imaging: a sparse-view imaging and the intensityweighted
region-of-interest (IWROI) imaging. IWROI imaging technique is particularly interesting because it can reduce
the imaging radiation dose substantially to the structures away from the imaging target, while allowing a stable solution
of the reconstruction problem in comparison with the interior problem. We used a total-variation (TV) minimization
algorithm that exploits the sparseness of the image derivative magnitude and can reconstruct images from sparse-view
data. In this study, we implemented an imaging mode that combines a sparse-view imaging and an ROI imaging. We
obtained promising results and believe that the proposed scanning approach can help reduce radiation dose to the patients
while preserving good quality images for applications such as image-guided radiation therapy. We are in progress of
applying the method to the real data.
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