Chemical constituents of Xuezhikang Capsula

Objective To study the chemical constituents of Xuezhikang Capsula. Methods Silica gel and Sephadex LH-20 were used to isolate the compounds, EI, FAB-MS, and 1 D and 2 D-NMR were used to identify the obtained compounds. Results Nine compounds were obtained from the capsula, they were charactered as dehydromonacolin K (Ⅰ), stigmasta-5, 22-dien-3β-ol (Ⅱ), monacolin K (Ⅲ), 3β-hydroxy-5α, 8β epidioxyergostera-6, 22-diene (Ⅴ), N-[1-(tetrahydro-5-oxofuran-2-yl)-ethyl] acetamide (Ⅵ), 7, 4′-dihydroxy-isoflavone (Ⅶ), 7, 4′-dihydroxyisoflavone-6-methoxyisoflavone (Ⅷ), 5, 7, 4′-trihydroxyiso-flavone (Ⅸ), erythritol (Ⅹ). Conclusion They are all obtained from the capsula except Ⅰ and Ⅲ for the first time, among them Ⅵ is a new natural compound.