An AIE probe for imaging mitochondria SO2-induced stress and its level in heat stroke

A probe MITO-TPE was developed for imaging mitochondrial SO2 with good selectivity, high sensitivity, and fast response. Cell imaging indicated that SO2 induced oxidative stress may cause damage to cells through O2•− bursting. MITO-TPE has been achieved imaging the misregulation of SO2 level in mitochondria during heat stroke for the first time.