Circulating tumor cell subsets and macrophage polarization to predict efficacy of cabozantinib in advanced prostate cancer with visceral metastases.

Edwin M. Posadas,Jie-Fu Chen,Manisha Tripathi,Yi-Tsung Lu,Alexander Montes,Ann Go,Alexander Ureno,Karen A. Cavassani,Margarit Sievert,Andre Rogatko,Suwicha Limvorasak,Amy Oppenheim,Nancy P. Moldawer,Leland W.K. Chung,Neil A. Bhowmick,Hsian-Rong Tseng,Robert A. Figlin

Circulating tumor cell subsets and macrophage polarization to predict efficacy of cabozantinib in advanced prostate cancer with visceral metastases.

2017

Edwin M. Posadas
Jie-Fu Chen
Manisha Tripathi
Yi-Tsung Lu
Alexander Montes
Ann Go
Alexander Ureno
Karen A. Cavassani
Margarit Sievert
Andre Rogatko
Suwicha Limvorasak
Amy Oppenheim
Nancy P. Moldawer
Leland W.K. Chung
Neil A. Bhowmick
Hsian-Rong Tseng
Robert A. Figlin

5031Background: The presence of VM in metastatic, castration-resistant prostate cancer (mCRPC) predicts poor survival. Cabozantinib (cabo) is a multi-kinase inhibitor that has clinical activity tha...

Keywords:

Macrophage polarization
Prostate cancer
Circulating tumor cell
Cancer research
Pathology
Medicine
Cabozantinib

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