Сравнительная оценка изменений буккального эпителия родильниц с врожденными пороками развития плода, проживающих на территориях химического загрязнения окружающей среды

The article presents comparative evaluation of alterations of buccal epithelium in puerperae aged from 20 to 30 years with and without inherent malformations of fetus (according rate of cytogenetic disorders, indicators of proliferation and destruction of nucleus) residing in territories with different level of chemical pollution of environment. It is established that in puerperae with inherent malformations of fetus the rate of cells with karyopyknosis is 1.3 times (p>0.05) and with karyolysis in 2.5 (p < 0.001) times higher than corresponding indicators in puerperae without inherent malformations of fetus. The received data can be used under individual examination of women planning pregnancy as one of criteria of detecting groups of assigned risk of development of malformations in fetus.