[Autoregulation of cerebral circulation: adaptation to hypertension and re-adaptation in response to antihypertensive treatment].

Abstract In chronic hypertension, autoregulation of cerebral blood flow (CBF) is adapted to high blood pressure. Thus in untreated hypertensive patients, the autoregulation curve is shifted towards higher pressure. With antihypertensive treatment autoregulation curve may be shifted back to the normal position or shift upward to the beneficially higher level of CBF. The effect of various antihypertensive drugs on CBF has been discussed.