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Cell injury inducer

2015 
An excellent cytotoxic activity and high safety maintained, including a domain comprising an antibody variable region having glypican 3 binding activity and a domain comprising an antibody variable region having T cell receptor complex binding activity Multispecific antigen binding molecules were found. Since the molecule of the present invention exhibits strong cytotoxicity to cells and tissues that express glypican 3, it becomes possible to produce new pharmaceutical compositions for treating or preventing various cancers.
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