Indocyanine Green Fluorescence-Navigated Sentinel Node Navigation Surgery (SNNS) for Cutaneous Malignant Melanoma and Extramammary Paget’s Disease

Sentinel node navigation surgery (SNNS) has been developed as a beneficial procedure to detect clinically-negative early regional lymphatic metastases in various types of skin cancers. Recently, a novel method was developed using a near-infrared imaging system to visualize indocyanine green (ICG)-induced fluorescence and to detect sentinel lymph nodes (SLN) in breast cancer. Herein, we describe the critical techniques of this new method in the patients with cutaneous melanoma and nonmelanoma skin cancers.