One-pot synthesis of salicylaldehyde containing biaryl frameworks via an aminocatalytic Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones

Abstract Salicylaldehyde containing biaryls are efficiently synthesized via an unprecedented amine promoted Diels-Alder-retro-Diels-Alder cascade reaction of ynals with 2-pyrones in good yields. The reaction is instrumentally metal-free, operationally simple and mild, and tolerates a diverse array of functional groups.