Secondary metabolites of the endophtic fungus Fusarium moniliforme ZSU-1 from rice.

The preponderant endophytic fungi of rice in Guangdong Province were Fusarium spp.In order to study the function of secondary metabolites from endophytic fungi on bio-control to rice paddy disease,a strain of endophtic fungus Fusarium moniliform ZSU-1 from sterily rice stem was ferment cultured,four secondary metabolites was isolated and purified by silica column and sephadex LH-20 chromatogram.On the basis of 1D、2D NMR and mass spectral data,there were fusaric acid(1),fusaric and 9,10-dehydrofusaric acids(1: 1)(2),beauvericin(3) and mannitol(4).The components 1 and 2 have strong antibacterial activities,they might be used for bio-control to rice paddy disease.