Mild and Efficient Synthesis of Isoindigo Derivatives Catalyzed by Lewis Acid
2016
Abstract A mild and efficient ZrCl 4 -catalyzed synthesis of isoindigo derivatives from isatins and indolin-2-ones in refluxing ethanol is described. A variety of new functionalized isoindigo derivatives are obtained by simple filtration. Lewis acid was first used as catalyst in the synthesis of isoindigo derivatives.
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