Alkylamides from pericarps of Zanthoxylum bungeanum

Abstract Ten unsaturated alkylamides were isolated from the pericarps of Zanthoxylum bungeanum . Three of them identified as (2 E ,4 E )-2′-hydroxy- N -isobutyl-2,4-tetradecadienamide (named tetrahydrobungeanool), (2 E ,4 E ,8 Z )-2′-hydroxy- N -isobutyl-2,4,8-tetradecatrienamide (named dihydrobungeanool) and (2 E ,4 E ,8 Z ,10 E ,12 E )-1′-isopropenyl- N -(2′-bisobutenyl)-2,4,8,10,12-tetradecapentaenamide (named dehydro-γ-sanshool), are novel compounds. The content of each compound in crude drugs was determine by HPLC.