Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

A. Marijke Keestra,Maria G. Winter,Josef J. Auburger,Simon P. Fräßle,Mariana N. Xavier,Sebastian E. Winter,Anita Kim,Victor Poon,Mariëtta M. Ravesloot,Julian F. T. Waldenmaier,Renée M. Tsolis,Richard A. Eigenheer,Andreas J. Bäumler

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

2013

A. Marijke Keestra
Maria G. Winter
Josef J. Auburger
Simon P. Fräßle
Mariana N. Xavier
Sebastian E. Winter
Anita Kim
Victor Poon
Mariëtta M. Ravesloot
Julian F. T. Waldenmaier
Renée M. Tsolis
Richard A. Eigenheer
Andreas J. Bäumler

Salmonella effector proteins trigger host innate immunity through the activation of small Rho GTPases, which, in turn, is sensed by the NOD1/2 signalling pathway.

Keywords:

Cdc42 GTP-Binding Protein
Hedgehog signaling pathway
HEK 293 cells
NOD1
Innate immune system
Effector
Nod1 Signaling Adaptor Protein
Cell biology
Signal transduction
Biology
RAC1
Virulence factor
RHOA

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