In situ structural analysis of the human nuclear pore complex

Alexander von Appen,Jan Kosiński,Lenore Sparks,Alessandro Ori,Amanda L. DiGuilio,Benjamin Vollmer,Marie-Therese Mackmull,Niccolò Banterle,Luca Parca,Panagiotis L. Kastritis,Katarzyna Buczak,Shyamal Mosalaganti,Wim J. H. Hagen,Amparo Andres-Pons,Edward A. Lemke,Peer Bork,Wolfram Antonin,Joseph S. Glavy,Khanh Huy Bui,Martin Beck

In situ structural analysis of the human nuclear pore complex

2015

The most comprehensive architectural model to date of the nuclear pore complex reveals previously unknown local interactions, and a role for nucleoporin 358 in Y-complex oligomerization.

Keywords:

Architectural model
Biophysics
Protein structure
Protein multimerization
Nuclear pore
Crystallography
Nucleoporin
In situ
Biology
RANBP2
Cytoplasm
Transport protein
Structural biology
Coated vesicle

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